Antibacterial effect of silver nanoparticles synthesized on polyvinyl alcohol

Silver nanoparticles synthesized on PVA (compound 1) and on PVA/silica (compound 2) were tested for antibacterial effect on E. coli, P. aeruginosa and S. aureus strains. The bactericidal effects of silver nanoparticles were compared based on diameter of inhibition zones in discs diffusion method, Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) as well as medium supplemented with different concentration of nanoparticles. The results showed the strong antibacterial effect of silver nanoparticles against tested bacteria, the MIC values for silver on PVA (compound 1) were 3.1 µg·ml‒1 for E. coli and 6.25 for P. aeruginosa and S. aureus. For silver nanoparticles on the PVA/silica complex (compound 2), MIC values were 6.25 and MBC 12.5 µg·ml‒1 for all investigated strains. Both tested silver nanoparticles compounds caused complete inhibition of growth of E. coli, P. aeruginosa and S. aureus at concentration 5 µg·ml‒1 in medium.

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Opracowanie ze środków MNiSW w ramach umowy 812/P-DUN/2016 na działalność upowszechniającą naukę.