Chemical Composition and Antibacterial activity of Essential Oil of Marrubium vulgare from Eastern Algeria

The essential oil from flowering Marrubium (Marrubium vulgare L.) an aromatic member of the Lamiaceae family, from Algeria, obtained by hydrodistillation, was analysed by GC/FID and GC/MS. The constituents were identified by their mass spectra and Kovats’ indices. Fivety (50) components in the oil of M. vulgare were identified. The results demonstrated that the major components of the essential oil were: 4,8,12,16-Tetramethyl heptadecan-4-olid (16.97 %), Germacrene D-4-ol (9.61 %), α- pinéne (9.37 %), Phytol (4.87 %), Dehydro-sabina ketone (4.12 %), Piperitone (3.27 %), δ-Cadinene (3.13 %), 1-Octen-3-ol (2.35 %) and Benzaldehyde (2.31 %). Essential oil of M vulgare was evaluated for its antibacterial activities against Gram-positive and Gram negative pathogenic bacteria: Bacillus subtilis, Micrococcus luteus, Escherichia coli and Klebsiella pneumoniae.