Time-resolved optical spectroscopy and imaging of breast

A fully automated system for time-resolved reflectance and transmittance spectroscopy from 610 to 1010 nm was developed and applied to the optical (absorption and scattering) characterization of breast tissue in vivo. From absorption spectra, information is derived on tissue content of oxy-, deoxyhemoglobin, water and lipids, while scattering spectra provide knowledge on tissue structure. A portable system for breast imaging at four wavelengths (683, 785, 912, and 975 nm) was also developed and is being tested in clinics for the detection and characterization of breast lesions (optical mammography).