Effect of non-modified and modified nanodiamond particles by Fenton reaction on human endothelial cells

Purpose: The use of carbon nanoparticles in medicine is increasing due to their high biocompatibility. Nanopowders are one of the best materials which can be used in medicine on medical implants and surgical tools. DPP (Diamond Powder Particles) obtained by different methods which can be expected to affect their properties, including biocompatibility, were compared. The aim of the present study was to compare the biocompatibility of Diamond Powder Particles (DPP) obtained by detonation method and graphite on the basis of their interactions with human endothelial cells. Design/methodology/approach: The effect of nanodiamonds on cell proliferation HUVEC-ST and production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) was studied. We used FT-IR Spectroscopy attributive chemical function groups. Findings: In this subject the material characterization of nanodiamond powders and influence on endothelial cells. Practical implications: Biological research with endothelial cells and nanodiamond powder are the introduction to application in human’s treatment. Originality/value: Nanodiamond powders with chemical modified surface.