Zielone metody przygotowania próbek do celu analizy chromatografią cieczową

In the context of green chemistry, modern sample preparation methods in liquid chromatography play a key role in minimizing environmental impact, reducing solvent consumption and reducing analysis time and costs. Analytical procedures related to sample preparation are an important step, both in terms of time consumption and the possibility of errors or contamination. One of the important trends in green methods is the use of direct chromatographic techniques, which eliminate the need to use solvents and other materials. Despite their benefits, there is a challenge in analyzing complex samples. In order to minimize these challenges, the focus was on miniaturization and automation of sample preparation processes. Techniques such as solid-phase extraction are gaining popularity, enabling efficient separation of analytes. Progress in the field of solid-phase microextraction and other modern techniques, such as extraction using a mobile sorption element or hollow fiber liquid phase microextraction, enable precise analysis while minimizing the consumption of solvents. The field of sample preparation is also being revolutionized by alternative solvents such as ionic liquids, supercritical fluids and deep eutectic solvents. Another important aspect is techniques that accelerate the extraction process, such as extraction assisted by microwave radiation and ultrasounds. Green sample preparation methods in liquid chromatography are moving towards a sustainable and efficient approach, using innovative techniques, minimizing solvent consumption and increasing automation. These advances are crucial to achieving green chemistry goals, reducing the ecological footprint and speeding up analytical processes.