Zespół ciężkiej gorączki z trombocytopenią

Severe fever with thrombocytopenia syndrome (SFTS), is an emerging infectious zoonotic disease caused by a new phlebovirus, namely Huaiyangshan banyangvirus (family Phenuiviridae, Bunyavirales). The disease presents various clinical manifestations, including high fever, gastrointestinal signs, neurological signs, thrombocytopenia, leukocytopenia, lymphadenopathy and multiple organ failure, shown by elevated levels of serum alanine aminotransferase, aspartate aminotransferase, creatine kinase, and lactate dehydrogenase. SFTSV is transmitted by a bush tick, Haemaphysalis longicornis, bites and human-tohuman transmission has also been reported. SFTSV attacks primarily goats, cattle, dogs, cats, pigs, deer, elks, wild boars, chickens, rodents and shrews, small insectivorous mammals, but the clinical manifestations of SFTS have been reported mainly in dogs and cats. Dogs and cats, which live in close contact with their owners, serve as important mediators for transmitting virus to humans. Effective therapies or vaccines are not yet available. This review describes the different aspects of virology, pathogenesis, epidemiology and clinical symptoms of SFTS in animals and also in humans.