Key factors in bone marrow transplant outcomes: statistical insights

This study examines critical factors affecting bone marrow transplant outcomes, focusing on the effect of increased doses of CD34+ cells/kg on patients’ overall survival time and quality of life without inducing adverse events. Using Statistica 13.3 software for analysis, the study examined the relationship between transplant success and various parameters such as disease type, recipient age, risk classification, and incidence of acute and chronic graft-versus-host disease (GVHD). Data from the UC Irvine Machine Learning Repository, comprising 187 pediatric patients undergoing allogeneic stem cell transplantation between 2000 and 2008, serve as the basis for this study. The significance of the factors in question was examined using Pearson’s chi-square test. The importance of CD34+ cell dose, the impact of risk group and recipient age, and the key role of GVHD management in the success of bone marrow transplants are noted.