Effects of intra-amygdaloid TRH injections on motor activity and dominant-submissive behavior in rats competing for water

Puciłowski O., Trzaskowska E., Jankowska E., Kostowski W., Kupryszewski G.: Effects of intra-amygdaloid TRH injections on motor activity and dominant-submissive behavior in rats competing for water. Acta Physiol. Pol. 1990, 41(1-3); 71-77. The effect of thyrotropin releasing hormone (TRH) microinjections into the central amygdala (10 g in 0.5 1 into each side) on locomotor activity, water intake and dominance behavior in a water competition test was investigated in male Wistar rats. TRH increased the general motility without altering the number of rearings. Intra-amygdaloid TRH injection to submissive rats resulted in a loss ol subordinate position in these animals in the water competition test. A tendency to decrease dominance followed the injection оf the peptide to the dominant animals. The effect of TRH in the dominance test does not appear to involve influence on the thirst drive as microinjection of the peptide did not change significantly the water consumption in thirsty rats.