Lack of association between Helicobacter pylori infection and biliary tract diseases

There are ambiguous results about the involvement of Helicobacter species in production of hepatobiliary diseases. is study was aimed to investigate any possible association between the presences of Helicobacter spp., their genotypes and occurrence of di"erent biliary diseases. Cultures of 102 bile samples for Helicobacter spp. did not show any growth, but the presence of Helicobacter genus specific DNA (16s rRNA gene) was detected in 3.92% of them. No significant association was found between development of the diseases and presence of the bacteria. All the Helicobacter genus positive samples belonged to H. pylori species and showed vacA+ (s1/m2), cagA– genotypes.