Influence of experimentalo diets on cholesterol and triglyceride levels of rabbit blood serum lipoproteins

Wehr, H., Naruszewicz, M., Nowicka, G. and Dziedziak, W.: Influence of experimental diets on cholesterol and triglyceride levels of rabbit blood serum lipoproteins. Acta physiol, pol., 1938. 39 (3): 202-206. Groups of rabbits were fed for six weeks various diets: standard died + ethanol, high-cholesterol diet and a high-cholesterol +: ethanol one. During the next six weeks every diet was supplemented with a fresh vegetable (carrot). Cholesterol and triglycerides were determined in the whole serum and in lipoprotein fractions. In rabbits fed standard diet ethanol caused a moderate elevation of VLDL cholesterol and triglyceride and LDL cholesterol levels. In animals on high-cholesterol diet cholesterol and triglyceride conćentrations in these fractions were very high. Simultaneous consumption of large amounts of cholesterol and of ethanol resulted in a greater rise of cholesterol concentration in the whole serum and in VLDL and LDL fraction than did high-cholesterol diet alone. Addition of carrot caused a pronounced reduction of serum cholesterol concentration in animals fed all kinds of diets. The reduction concerned mainly VLDL.