Parameters of shared input and modulations of activity of pairs of sympathetic renal neurons

This study was carried out on sympathetic renal fibers of anaesthetised rabbits. Shared input assessed by cross-correlation analysis was found in 159 pairs of neurons in control conditions and in 128 during increased blood pressure. The width of cross-correlogram peak was 237.57±5.54 ms in control conditions and 249.97±7.13 ms during elevated blood pressure. The peak height was respectively 4.03±0.14 spikes/s and 4.39±0.23 spikes/s. Geometric mean of frequency of discharge of neuronal pairs was 1.17±0.04 spikes/s and 0.93±0.04 spikes/s. Geometric mean of cardiac modulation was weak 33.56±1.18% and significantly correlated with geometric mean of frequency of discharge and correlogram width in control conditions. The respiratory modulation of pairs of neurons was strong – respectively 78.63±0.85% and 88.29±0.95% – and was significantly related with geometric mean of frequency of discharge, correlogram width and peak height in resting conditions.