Wplyw cynku na nagromadzanie sie kadmu w wybranych tkankach szczura w doswiadczalnym zatruciu siarczanem kadmu

Badano wpływ cynku na stężenie kadmu w surowicy, wątrobie, nerce, śledzionie i kości udowej szczurów narażonych na 5 i 50 mg Cd/dm3 w wodzie do picia. Stwierdzono, że cynk zastosowany łącznie z 50 mg Cd/dm3 w wodzie zmniejszał toksyczność kadmu, obniżając jego stężenie w surowicy, wątrobie i nerce.

The effects of zinc on cadmium accumulation in rats examined. Male Wistar rats (n = 54) were divided into 3 groups. Group 1 (controls) were receiving deionized water, groups 2 and 3 were receiving 5 ppm and 50 ppm cadmium as cadmium sulphate in deionized drinking water for 8 weeks. Groups 2 and 3 were each divided into subgroups A, B, C, which were given zinc simultaneously with cadmium (8 weeks) or after termination of cadmium exposure (2 weeks). Zinc, when administered both simultaneously with cadmium and after exposure to 5 ppm Cd, decreased serum and spleen Cd concentration and increased its removal in urine. Zinc administered simultaneously with 50 ppm Cd was observed to exert a protective action resulting in decreased serum, liver, and kidney Cd concentration.