Grelina i motylina - podobienstwa i roznice w regulacji aktywnosci motorycznej przewodu pokarmowego

Ghrelin and motilin were compared with regards to their effects on gastrointestinal motility. The structure of their molecules is not very different and they act via similar receptors. Both induce phase three of MMC and enhance contractions during the interdigestive state. Their action can occur via central or peripheral mechanisms, mostly as neuropeptides, although direct action on smooth muscles cannot be excluded. However, the spectrum of ghrelin action is broader and also comprises the digestive period. The role of ghrelin in the gastrointestinal tract is substantial and its action seems to be physiological. Ghrelin is a new hormone-candidate in the gut.