Wplyw niskich stezen aflatoksyn na aktywnosc trypsyny i lipazy trzustkowej

W modelowych badaniach in vitro wykazano stymulujący wpływ niskich stężeń aflatoksyn B1, B2, G1, i G2 na aktywność trypsyny i lipazy trzustkowej.

In vitro tests have demostrated that contamination of food products with aflatoxins at levels found in the consumed food may significantly excite steapsin activity and insignificantly stimulate trypsin activity. The degree of trypsin activation in the presence of aflatoxins B1, B2, G2 and G2 at 3 x 10-6 to 3 x 102 ng/cm3 varied from 12% for aflatoxin G2 to 27% for aflatoxin B2. The increase of the steapsin activity at the same aflatoxin concetration range was much higher. The highest values (119% increase) was obtained for aflatoxin G2 samples at 3 x 102 ng/cm3, while for aflatoxins B1 and B2 increased activity was observed at the 70% —90% range.