Mitochondrial permeability to ions induced by dibenzodioxines and dibenzofuranes. A simple method to measure ion permeability in membranes

This paper proposes a method to demonstrate that 123789 Dibenzodioxine and 2378 Dibenzofurane enhance membrane permeability to the ions in mitochondria from rat liver. The procedure can be employed: i) as a general method to assess the enhancement of membrane permeability by toxic compounds, ii) to study the decrease in conductivity of carrier-systems induced by inhibitors of transport, and iii) to study the behaviour of ion-carrier systems which are potentially dependent on biological membranes.