Udzial hemolizy w rozwoju zaburzen nerek i watroby u psow z babeszjoza

The aim of the study was to evaluate the influence of natural haemolysis on the state of kidneys and livers in dogs suffering from babesiosis. Two groups of dogs were used in the study - 75 dogs with babesiosis and 20 healthy dogs as the control group. Besides evaluating the health status, direct and indirect laboratory diagnostics were performed: haemolysis and anemia intensification degree by erythrocytes mean count, haematocrite, hemoglobin blood, serum and urine concentration and kidney and liver state by urea, creatinine and bilirubin mean serum concentration, and serum activity of alanine transaminase. Dogs with babesiosis showed various clinical signs of the disease as well as consistent intravascular haemolysis, but of different intensity and rarely causing anemia. The study indicated, above all, the varied effect of hemoglobin and its metabolites released by haemolysis on the development of kidney and liver alterations, which, in turn, depended on the disease pattern and metabolic state of the animal.