Chemical synthesis of dolichyl phosphates, their analogues and derivatives and application of these compounds in biochemical assays

Several methods for simple and efficient chemical synthesis of dolichyl phosphates and their an-alogues and derivatives are briefly summarized with a special emphasis on chemical modifica-tion of phosphoryl group and preparation of dolichyl phosphates labelled at the ω-end and at the γ-isoprene unit of the isoprene chain by fluorescent groups, 2-aminopyridine and 1-aminon-aphtalene residues. Additionally, data on biochemical assays with application of the compounds mentioned above are presented.