Charakterystyka szczepow Neisseria meningitidis izolowanych od osob z objawowym zakazeniem meningokokowym w latach 1995-2000 w Polsce

Przedstawiono wyniki fenotypowej i genotypowej analizy 179 szczepów N. meningitidis oraz określono ich wrażliwość na wybrane antybiotyki i chemioterapeutyki. Wśród zbadanych meningokoków dominowały szczepy o fenotypie B:22:P1.14.

Phenotype and genotype identification of 179 Neisseria meningitidis strains isolated from cerebrospinal fluid or blood of patients with meningococcal infection, hospitalized in Poland, was performed. This is the first analysis of that type conducted in Poland. We analyzed strains collected in 1995-2000 from laboratories located all over the country. Phenotype Neisseria meningitidis B:22:P1.14 was the predominant among analyzed invasive strains in Poland. Type 22 is characteristic to most of the strains isolated in our country. No strain from analyzed group belonged to known epidemic clusters. One penicillin resistant strain (MIC=2 mg/l) and about 27% strains with decreased susceptibility to penicillin (0.1 =