The effect of titanium alloy modified with a-C:N:H and a-SiCxNY(H) coatings on adhesion and immune response of human osteoblast-like MG-63 cells

The study was conducted in order to determine the effects of modified titanium alloy (Ti-6Al-4V) surfaces on the biological response of a human osteoblast-like cell line. MG-63 cells were cultured on disk-shaped Ti-alloys: unmodified, and covered with a-C:N:H or a-SiCxNy(H) layers. Interactions between materials and cells were examined through determination of cells adhesion and secretion of cytokines involved in the development of immune response.

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The study was supported by research grant no. 215/ KF/2007 in the Academy of Physical Education in Cracow.