Physical aspects of selected medical diagnosis methods using radiation

Radioisotope technique allows noninvasive medical diagnosis such as diagnostication of Helicobacter pylori (H. pylori) infection by using urea laballed with C-14 and intraoperative control of sentinel node in breath cancer with use of nanocoloid labelled with Tc-99m. The knowledge of radiotracer transport and internal radiation hazard enable to improve medical diagnosis methods. The urea breath test (UBT) results have been used to apply compartmental modelling for determining severity and localisation of the Helicobacter pylori infection. The water imaging phantom of breast has been elaborated to prepare the application of a hand-held gamma probe Modelo-2 in an intraoperative control of sentinel node in breath cancer (RIGS - RadioImmunoguided Surgery).