Gas-Liquid Chromatographic Interactions for Twelve benzene-Derived Chemical Functions on Twelve Polar Stationary Phases

Linear solvation energy relationship (LSER) was used to describe the solute-solvent interactions of benzene and twelve derivatives on 12 stationary phases taken from literature. The hydrogen-bond interactions between the basic solute and the acid solvent were negligible, the more relevant interactions being cavity-formation/dispersion and the dipolar interactions. The effect of the polarity of both the stationary phase (solvent) and the solute (chemical function) on interactions has been investigated. The dipolar interaction increases for each solute with increasing phase polarity and for each phase with increasing solute polarity, whereas the cavity-formation/dispersion interaction decreases with increasing stationary phase polarity. The plots of the cavity-foration/dispersion and of dipolar interaction increments between chemical functions and parent benzene molecule versus stationary phase polarity confir the above trends.