Experimental measurements of friction forces on the tissue in prababilistic view

This paper is devoted to stochastic determination of values of friction forces generated during hydro-dynamical flow of viscid-elastic nutrition liquid in thin boundary layer present on surface of human joint cartilage sample during its growing in a bio-reactor. Taking into account the need for tissue cultivation, this paper presents the detail results of measurements of friction forces occurring on the cartilage sample during the tissue cultivation. Results of irregularities of human joint cooperating surfaces are applied to the friction simulation during the cartilage cultivation in bioreactor. This paper has been prepared based on the objective of European Project MTKD-CT-2004-517226 to represent the methodology and goal of the idea described in and make possible wider discussion on this subject for further developments during the realization. Stages of joint cartilage development and growth in bio-reactor of random character, analysis of joint cartilage surface nano- roughness, the used cartilage of thigh bone head of human hip joint, distributions of probability density function of the random changes in height of nutrition liquid boundary layer on surface of the tissue growing in bio-reactor, control of friction forces and geometrical parameters of natural cartilage surface are presented in the paper.