Synthesis, Spectral Characterization and Biological Studies of Lanthanum(III) Complexes with 3-Substituted-4-Amino-5-Mercapo-1,4-Triazoles Schiff Bases

Some lanthanum(III) complexes have been synthesized by reacting lanthanum(III) metal salt with Schiff bases derived from 3-substituted-4-amino-5-mercapto-1,2,4-triazole and glyoxal/ biacetyl/ benzyl. All these complexes are not soluble in common organic solvents. However sparingly soluble in DMF and DMSO. The chemical analysis of the complexes confirmed to the stoichiometry of the type La(III)LNO3•H2O. La(III)LCl•H2O and La(III)LNCS•H2O respectively. The chelation of the complexes has been proposed in the light of analytical, spectral studies. The measured molar conductance values indicate that, the complexes are non-electrolytes. The Schiff bases and their complexes have been screened for their antibacterial and antifungal activities. The results of these studies show the metal complexes to be more antibacterial and antifungal as compared to the uncomplexed coumarins. lanthanum(III) complexes.