Uterine myoelectrical activity as biomarker of successful induction with Dinoprostone: Influence of parity

The prolonged latent phase of Induction of Labour (IOL) is associated with increased risks of maternal mortality and morbidity. Electrohysterography (EHG) has outperformed traditional clinical measures monitoring labour progress. Although parity is agreed to be of particular relevance to the success of IOL, no previous EHG-related studies have been found in the literature. We thus aimed to identify EHG-biomarkers to predict IOL success (active phase of labour in ≤ 24 h) and determine the influence of the myoelectrical response on the parity of this group. Statistically significant and sustained differences between the successful and failed groups were found from 150 min in amplitude and non-linear parameters, especially in Spectral Entropy and in their progression rates. In the nulliparousparous comparison, parous women showed statistically significantly higher amplitude progression rate. These biomarkers would therefore be useful for early detection of the risk of induction failure and would help to develop more robust and generalizable IOL successprediction systems.

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Opracowanie rekordu ze środków MEiN, umowa nr SONP/SP/546092/2022 w ramach programu "Społeczna odpowiedzialność nauki" - moduł: Popularyzacja nauki i promocja sportu (2022-2023)