Calcium deposition and osteogenic differentiation data from tempeh, daidzein, and probiotics in an artificial gastrointestinal tract

This research collection explores the impact of daidzein, tempeh, and the probiotic Lactobacillus acidophilus on calcium deposition and bone health, with a specific focus on their bioavailability and osteogenic potential in a simulated gastrointestinal environment. The studies utilize advanced cell models, including Caco-2 epithelial and Saos-2 osteoblast-like cells, to simulate intestinal absorption and bone formation mechanisms. 

The first study in this series evaluates the bio accessibility of calcium when combined with tempeh, daidzein, and probiotics, followed by assessing their effects on calcium deposition in bone cells. Findings reveal insights into the proliferation and differentiation of osteoblast-like cells, highlighting the potential of these bioactive compounds to support bone health beyond traditional mineral supplements. This collection is valuable for researchers and healthcare professionals interested in innovative nutritional strategies for bone health, providing foundational data on the interactions between plant-based bioactives and probiotics in promoting bone mineralization.