Replication data for: The clinical infection with pigeon circovirus (PiCV) leads to lymphocyte B apoptosis but has no effect on lymphocyte T subpopulation

Data included in this collection are connected with the article "The clinical infection with pigeon circovirus (PiCV) leads to lymphocyte B apoptosis but has no effect on lymphocyte T subpopulation" in PLOS Pathogens.

The study was conducted with 56 pigeons. Based on PiCV infectious and health status, they were divided into the following groups: PiCV-positive but showing (group S) or not (group I) non-specific clinical symptoms, and asymptomatic pigeons negative for PiCV (group H). The percentage and apoptosis of T CD3⁺ and B IgM⁺ splenocytes (flow cytometry); the expression of CD4, CD8, and IFN-γ genes in splenic mononuclear cells (qPCR); the number of PiCV viral loads in the bursa of Fabricius (ddPCR); and the level of anti-PiCV IgY in serum (ELISA) were analyzed.