Data for the article entitled “Zeolitic Imidazolate Framework‑8 (ZIF-8) modified titanium alloy for controlled release of drugs for osteoporosis”

Files include the data presented in the manuscript entitled "Zeolitic Imidazolate Framework‑8 (ZIF-8) modified titanium alloy for controlled release of drugs for osteoporosis" by M. Sandomierski et al. (https://doi.org/10.1038/s41598-022-13187-0).

The aim of this work was to prepare a biocompatible implant material that enables the release of drug for osteoporosis—risedronate. To achieve this goal, a titanium implant coated with a biocompatible Zeolitic Imidazolate Framework 8 (ZIF-8) layer was prepared that promotes osseointegration at the bone-implant interface. The drug was released in small doses for 16 h, which may help patients recover immediately after surgery. This is the first case of using ZIF-8 on the surface of the titanium alloy as carrier that releases the drug under the influence of body fluids directly at the site of the disease. It is an ideal material for implants designed for people suffering from osteoporosis.

Data (.txt) includes:

1) High-resolution XPS spectra of zinc, nitrogen, and phosphorous for the Ti ZnTit-ZIF-8 and Ti-ZnTitZIF-8-RSD samples. (Figure 5.)

2) FT-IR results. (Figure 6.)

3) Total release of risedronate from the surface of Ti6Al4V alloys coated with ZIF-8. (Figure 11.)