Title for the dataset:
Divergent Impact of Endotoxin Priming and Endotoxin Tolerance on Macrophage Responses to Cancer Cells
GENERAL INFORMATION
Language: English
Principal investigator:
Roy Konkonika
https://orcid.org/0000-0002-3742-5649
Associate or co-investigators:
Wrotek Sylwia
https://orcid.org/0000-0001-8744-7822
Maciejewski Bartosz
https://orcid.org/0000-0003-3496-8805
Contact person for questions:
Roy Konkonika konkonika.roy@doktorant.umk.pl
Maciejewski Bartosz bartosz.maciejewski@umk.pl
Date and place of data collection:
2022-2025
Department of Immunology
Faculty of Biological and Veterinary Sciences
Nicolaus Copernicus University in Toruń
Lwowska 1, 87-100 Toruń, Poland
Keywords: endotoxin tolerance, cancer, M1/M2 phenotype, immunosuppression, tumor microenvironment
Funding
NCN PRELUDIUM BIS 2 nr 2020/39/O/NZ5/00915
Licence: CC-BY 4.0
DATA DESCRIPTION
The dataset includes results from in vitro interactions between immune cells (RAW 264.7 macrophages) and the tumor microenvironment (4T1 cells) under endotoxin tolerance (ET) conditions.
It contains spreadsheets, pictures, PDF and FCS files.
Details regarding materials and methods are described in the article:
Roy K, Jędrzejewski T, Sobocińska J, Spisz P, Maciejewski B, Hövelmeyer N, Passeri B, Wrotek S. Divergent impact of endotoxin priming and endotoxin tolerance on macrophage responses to cancer cells. Cell Immunol. 2025 Mar 1;411-412:104934.
https://doi.org/10.1016/j.cellimm.2025.104934
