Green-Emitting 4,5-Diaminonaphthalimides in Activity-Based Probes for the Detection of Thrombin

Szczegóły
Opis

Tytuł:: Green-Emitting 4,5-Diaminonaphthalimides in Activity-Based Probes for the Detection of Thrombin
Autorzy:: Gryko, Daniel T.
Bousquet, Manon H. E.
Jacquemin, Denis
Krzeszewski, Maciej
Modrzycka, Sylwia
Drąg, Marcin
Współwytwórcy:: CEISAM UMR CNRS 6230, Nantes University
Institute of Organic Chemistry, Polish Academy of Sciences
Department of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology
Data publikacji:: 2022
Wydawca:: American Chemical Society
Język:: angielski
ISBN, ISSN:: 15237060
Prawa:: http://creativecommons.org/licenses/by/4.0/
Linki:: https://depot.ceon.pl/handle/123456789/22307 Link otwiera się w nowym oknie
Dostawca treści:: Repozytorium Centrum Otwartej Nauki
: Inne

Przejdź do źródła

The natures of electron-donating groups as well as the bridge between them determine the fate of substituted 1,8-naphthalimide molecules in the excited state. An activity-based probe constructed from a selective peptide sequence, a reactive warhead, and the brightest green-emitting fluorophore displays impressive performance for thrombin protease detection in a newly constructed series of 1,8-naphthalimides.

Foundation for Polish Science (TEAM POIR.04.04.00-00-3CF4/16-00) ; European Union’s Horizon 2020 research and innovation programme under Grant Agreement 860762 ; TEAM program of the Foundation for Polish Science and cofinanced by the European Union under the European Regional Development Fund (TEAM/2017-4/32)

Informacja

Green-Emitting 4,5-Diaminonaphthalimides in Activity-Based Probes for the Detection of Thrombin