Clinical and epidemiological aspects of acute pancreatitis ‒ 10 years of single-center experience

Background In recent years we can observe an increased incidence of acute pancreatitis (AP). Material and methods Retrospective clinical data analysis of 370 patients with AP, hospitalized between 2007 and 2016 at our Department. Results AP was diagnosed during 406 hospitalizations in 370 patients [average age 52.15 (21-93), 237(64.05%) male]. AP of high clinical severity was diagnosed in 60/370 (16.22%) patients. Average time of hospitalisation was 16.13 (1-121) days. Mortality was 12/406 (2.96%). A complication of AP in form of parapancreatic fluid reservoirs was diagnosed in 202/406 (54.59%) cases. A shorter time of hospitalisation was proven and a lower mortality of the patients in the later phase of the study (2012-2016).The analysis of patients' blood tests revealed that patients with severe AP have significantly elevated levels of inflammatory parameters and amylase comparing to group with mild and moderate AP during the first days of hospitalisation. Conclusions The development of conservative treatment options for AP, especially in early stages of the illness, has significantly shortened the duration of hospitalisation of patients with AP at our Department.