Tytuł pozycji:
NEUROPATHOLOGY OF MANGANESE INTOXICATION IN RATS. PRELIMINARY COMMUNICATION
In search for an experimental model of Parkinsonian syndrom pathomorphological studies were carried out on 12 rats subjected to manganese intoxication. Manganous chloride (in totaldosis of 240 mg/kg of body weight, counted of Mn++) was intravenously injected in 7 dosesduring the period of 4 weeks. For following 4 weeks animals were not subjected to any experimental treatment. The animals were sacrificed by intracardiac perfusion with neutral 10% formaline. Brains, livers and kidneys were studied histologically.