Gross tumour volume comparison in oropharynx carcinomas using different intelligent imaging software : a retrospective analysis

Purpose: To compare gross tumour volume (GTV) in oropharynx carcinomas using different intelligent imaging software and to evaluate which method is more reliable for tumour volume definition in comparison with 3D ProSoma software. Material and methods: We retrospectively studied 32 patients with histopathologically confirmed oropharynx carcinomas on dual-source computed tomography (CT) (all patients underwent multislice CT examination after applying 75 ml iodinated non-ionic contrast media). One radiologist calculated the tumour volume - manually measuring tumour length (L), width (W), and height (H) - and then calculated the tumour volume using the formula 0.5236 × L × W × H. The other radiologist used the syngo.CT-Liver-Analysis software to calculate the tumour volumes. Both volume measuring methods were compared with the 3D ProSoma software, which is used by radiotherapists to calculate tumour volumes. Graphpad Prism software was used for statistical data. Results: syngo.CT-Liver-Analysis software for gross tumour volume determination has greater reliability than the standard manual method with Syngo Plaza in comparison with the 3D ProSoma software. Conclusions: syngo.CT-Liver-Analysis software is a reliable tool for GTV calculation, with a high correlation score, like that of radiotherapeutic 3D ProSoma software.