Lichen planus coexisting with diabetes mellitus and hypertension (Grinspans syndrome) : description of two cases

Introduction: Lichen planus is a chronic skin and oral mucosa disease. Coexistence of the oral form of lichen planus with diabetes and hypertension was described for the first time by Grinspan in 1963. Case description: Two cases of the occurrence of lichen planus in patients with diagnosed diabetes and hypertension (Grinspan’s syndrome) are presented. In the first case, diabetes and hypertension treatment were accompanied by lesions in the oral cavity and on the skin of shins. In the other case, lichen planus type lesions were manifested only in the oral cavity. Conclusions: The aetiology of lichen planus remains unclear to some extent. Detailed diagnostics is based on clinical examination, general medical history and histopathological findings. The risk of malignant transformation of oral lichen planus ranges from 0.4 to 5.3% and it regards mainly the erosive form. Regular follow-up visits and oncological vigilance constitute an inseparable part of treatment.