Altruism is defined as an action that decreases the lifetime direct fitness of an actor and benefits one or more recipients. This phenomenon, which is generally difficult to understand and explain, requires special research attention. The subject of this review, rescue, is a type of altruistic behavior in which the actor puts itself at risk to save another individual, the recipient, that is in danger. The highest numbers of published empirical works have been devoted to rescue behavior in ants and they have enormous potential for further study. We review studies devoted to the subject and group them into four main areas of research on ant rescue actions: (1) variation in rescue behavior activity on a between-individual scale, (2) factors contributing to the evolution of rescue behavior on a between-species scale, (3) rescue behavior releaser signals and (4) rescue behavior benefits and costs. We highlight the progress in research on rescue behavior in ants, indicate that this behavior is probably much more common than previously thought yet thus far demonstrated in only a few species, and uncover research gaps and open questions that remain unexplored. We additionally point out some gaps in knowledge that become evident when research devoted to rescue behavior in rats, the second most studied group of animals in this context, is briefly overviewed. We hope to help navigate among studies on rescue behavior and provide the most up-to-date summary of the relevant literature. Moreover, we hope to encourage and facilitate researchers in behavioral ecology and other subdisciplines to further experimentally analyze rescue behavior, not only in ants but also in other taxa.