Entropy production and collective phenomena in biological channel gating

We investigate gating kinetics of biological channels influenced by conformational changes within the membrane proteins forming the module, and subject to a coupling with other similar units. By introducing elements of stochastic thermodynamics, we analyze the information flow and associated entropy production during gating cycle of a single channel. In the second part of this paper, synchronized kinetics of multiple units of that type is analyzed in terms of Kuramoto’s theory.